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Monitoring Solution Structures of Peroxisome Proliferator-Activated Receptor β/δ upon Ligand Binding
Peroxisome proliferator-activated receptors (PPARs) have been intensively studied as drug targets to treat type 2 diabetes, lipid disorders, and metabolic syndrome. This study is part of our ongoing efforts to map conformational changes in PPARs in solution by a combination of chemical cross-linking...
Autores principales: | Schwarz, Rico, Tänzler, Dirk, Ihling, Christian H., Sinz, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798536/ https://www.ncbi.nlm.nih.gov/pubmed/26992147 http://dx.doi.org/10.1371/journal.pone.0151412 |
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