cMET inhibitor crizotinib impairs angiogenesis and reduces tumor burden in the C3(1)-Tag model of basal-like breast cancer

Epidemiologic studies have associated obesity with increased risk of the aggressive basal-like breast cancer (BBC) subtype. Hepatocyte growth factor (HGF) signaling through its receptor, cMET, is elevated in obesity and is a pro-tumorigenic pathway strongly associated with BBC. We previously reporte...

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Detalles Bibliográficos
Autores principales: Cozzo, Alyssa J., Sundaram, Sneha, Zattra, Ottavia, Qin, Yuanyuan, Freemerman, Alex J., Essaid, Luma, Darr, David B., Montgomery, Stephanie A., McNaughton, Kirk K., Ezzell, J. Ashley, Galanko, Joseph A., Troester, Melissa A., Makowski, Liza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4799044/
https://www.ncbi.nlm.nih.gov/pubmed/27057482
http://dx.doi.org/10.1186/s40064-016-1920-3

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