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PARP-1 inhibition influences the oxidative stress response of the human lens

Poly(ADP-ribose) polymerase-1 (PARP-1) is best characterised for its involvement in DNA repair. PARP-1 activity is also linked to cell fate, confounding its roles in maintaining genome integrity. The current study assessed the functional roles of PARP-1 within human lens cells in response to oxidati...

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Detalles Bibliográficos
Autores principales: Smith, Andrew J.O., Ball, Simon S.R., Bowater, Richard P., Wormstone, I. Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4799059/
https://www.ncbi.nlm.nih.gov/pubmed/26990173
http://dx.doi.org/10.1016/j.redox.2016.03.003