BIOMATERIAL IMPLANTS IN BONE FRACTURES PRODUCED IN RATS FIBULAS

To evaluate the importance of collagen and hydroxyapatite in the regeneration of fractures experimentally induced in the fibulas of rats. Method: 15 rats were used. These were subjected to surgery to remove a fragment from the fibula. This site then received a graft consisting of a silicone tubes fi...

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Detalles Bibliográficos
Autores principales: Shirane, Henrique Yassuhiro, Oda, Diogo Yochizumi, Pinheiro, Thiago Cerizza, Cunha, Marcelo Rodrigues da
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Artigo Original
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4799216/
https://www.ncbi.nlm.nih.gov/pubmed/27047813
http://dx.doi.org/10.1016/S2255-4971(15)30439-0
Descripción
Sumario:To evaluate the importance of collagen and hydroxyapatite in the regeneration of fractures experimentally induced in the fibulas of rats. Method: 15 rats were used. These were subjected to surgery to remove a fragment from the fibula. This site then received a graft consisting of a silicone tubes filled with hydroxyapatite and collagen. Results: Little bone neoformation occurred inside the tubes filled with the biomaterials. There was more neoformation in the tubes with collagen. Conclusion: The biomaterials used demonstrated biocompatibility and osteoconductive capacity that was capable of stimulating osteogenesis, even in bones with secondary mechanical and morphological functions such as the fibula of rats.

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