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BIOMATERIAL IMPLANTS IN BONE FRACTURES PRODUCED IN RATS FIBULAS
To evaluate the importance of collagen and hydroxyapatite in the regeneration of fractures experimentally induced in the fibulas of rats. Method: 15 rats were used. These were subjected to surgery to remove a fragment from the fibula. This site then received a graft consisting of a silicone tubes fi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4799216/ https://www.ncbi.nlm.nih.gov/pubmed/27047813 http://dx.doi.org/10.1016/S2255-4971(15)30439-0 |
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author | Shirane, Henrique Yassuhiro Oda, Diogo Yochizumi Pinheiro, Thiago Cerizza Cunha, Marcelo Rodrigues da |
author_facet | Shirane, Henrique Yassuhiro Oda, Diogo Yochizumi Pinheiro, Thiago Cerizza Cunha, Marcelo Rodrigues da |
author_sort | Shirane, Henrique Yassuhiro |
collection | PubMed |
description | To evaluate the importance of collagen and hydroxyapatite in the regeneration of fractures experimentally induced in the fibulas of rats. Method: 15 rats were used. These were subjected to surgery to remove a fragment from the fibula. This site then received a graft consisting of a silicone tubes filled with hydroxyapatite and collagen. Results: Little bone neoformation occurred inside the tubes filled with the biomaterials. There was more neoformation in the tubes with collagen. Conclusion: The biomaterials used demonstrated biocompatibility and osteoconductive capacity that was capable of stimulating osteogenesis, even in bones with secondary mechanical and morphological functions such as the fibula of rats. |
format | Online Article Text |
id | pubmed-4799216 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-47992162016-04-04 BIOMATERIAL IMPLANTS IN BONE FRACTURES PRODUCED IN RATS FIBULAS Shirane, Henrique Yassuhiro Oda, Diogo Yochizumi Pinheiro, Thiago Cerizza Cunha, Marcelo Rodrigues da Rev Bras Ortop Artigo Original To evaluate the importance of collagen and hydroxyapatite in the regeneration of fractures experimentally induced in the fibulas of rats. Method: 15 rats were used. These were subjected to surgery to remove a fragment from the fibula. This site then received a graft consisting of a silicone tubes filled with hydroxyapatite and collagen. Results: Little bone neoformation occurred inside the tubes filled with the biomaterials. There was more neoformation in the tubes with collagen. Conclusion: The biomaterials used demonstrated biocompatibility and osteoconductive capacity that was capable of stimulating osteogenesis, even in bones with secondary mechanical and morphological functions such as the fibula of rats. Elsevier 2015-12-12 /pmc/articles/PMC4799216/ /pubmed/27047813 http://dx.doi.org/10.1016/S2255-4971(15)30439-0 Text en © 2010 Sociedade Brasileira de Ortopedia e Traumatologia http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Artigo Original Shirane, Henrique Yassuhiro Oda, Diogo Yochizumi Pinheiro, Thiago Cerizza Cunha, Marcelo Rodrigues da BIOMATERIAL IMPLANTS IN BONE FRACTURES PRODUCED IN RATS FIBULAS |
title | BIOMATERIAL IMPLANTS IN BONE FRACTURES PRODUCED IN RATS FIBULAS |
title_full | BIOMATERIAL IMPLANTS IN BONE FRACTURES PRODUCED IN RATS FIBULAS |
title_fullStr | BIOMATERIAL IMPLANTS IN BONE FRACTURES PRODUCED IN RATS FIBULAS |
title_full_unstemmed | BIOMATERIAL IMPLANTS IN BONE FRACTURES PRODUCED IN RATS FIBULAS |
title_short | BIOMATERIAL IMPLANTS IN BONE FRACTURES PRODUCED IN RATS FIBULAS |
title_sort | biomaterial implants in bone fractures produced in rats fibulas |
topic | Artigo Original |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4799216/ https://www.ncbi.nlm.nih.gov/pubmed/27047813 http://dx.doi.org/10.1016/S2255-4971(15)30439-0 |
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