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Cellular forces and matrix assembly coordinate fibrous tissue repair

Planar in vitro models have been invaluable tools to identify the mechanical basis of wound closure. Although these models may recapitulate closure dynamics of epithelial cell sheets, they fail to capture how a wounded fibrous tissue rebuilds its 3D architecture. Here we develop a 3D biomimetic mode...

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Detalles Bibliográficos
Autores principales: Sakar, Mahmut Selman, Eyckmans, Jeroen, Pieters, Roel, Eberli, Daniel, Nelson, Bradley J., Chen, Christopher S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4799373/
https://www.ncbi.nlm.nih.gov/pubmed/26980715
http://dx.doi.org/10.1038/ncomms11036