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Cellular forces and matrix assembly coordinate fibrous tissue repair
Planar in vitro models have been invaluable tools to identify the mechanical basis of wound closure. Although these models may recapitulate closure dynamics of epithelial cell sheets, they fail to capture how a wounded fibrous tissue rebuilds its 3D architecture. Here we develop a 3D biomimetic mode...
Autores principales: | Sakar, Mahmut Selman, Eyckmans, Jeroen, Pieters, Roel, Eberli, Daniel, Nelson, Bradley J., Chen, Christopher S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4799373/ https://www.ncbi.nlm.nih.gov/pubmed/26980715 http://dx.doi.org/10.1038/ncomms11036 |
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