Cargando…

EFFECT OF LOW-LEVEL LASER (GAAS, 904HM) FOR BONE REPAIR ON FRACTURES IN RATS

Objective: To analyze the effects of low-level laser therapy (GaAs, 904 nm) for bone repair on tibial fractures in rats. Methods: Forty rats were divided into four groups of 10 animals: control group without fracture (CG); fracture group without treatment (EG II); fracture group treated with laser a...

Descripción completa

Detalles Bibliográficos
Autores principales: Léo, Jorge Alfredo, Cunha, Alessanda da, de Oliveira, Elias Félix, Prado, Reuder Pereira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4799407/
https://www.ncbi.nlm.nih.gov/pubmed/27042627
http://dx.doi.org/10.1016/S2255-4971(15)30092-6
_version_ 1782422340856971264
author Léo, Jorge Alfredo
Cunha, Alessanda da
de Oliveira, Elias Félix
Prado, Reuder Pereira
author_facet Léo, Jorge Alfredo
Cunha, Alessanda da
de Oliveira, Elias Félix
Prado, Reuder Pereira
author_sort Léo, Jorge Alfredo
collection PubMed
description Objective: To analyze the effects of low-level laser therapy (GaAs, 904 nm) for bone repair on tibial fractures in rats. Methods: Forty rats were divided into four groups of 10 animals: control group without fracture (CG); fracture group without treatment (EG II); fracture group treated with laser at 10 J/cm(2) (EG III); and fracture group treated with laser at 15 J/cm2 (EG IV). The fracture was produced surgically and the treatment lasted 45 days, done on alternate days. After treatment completion, the rats were sacrificed. The tibias were radiographed and subjected to mechanical three-point flexion tests in order to evaluate the maximum force (N) required to break them. Results: The observed maximum force values (N) were: control group (CG) of 51.5 N ± 7.9 N; EG II 17.2 N ± 7.8 N; EG III 16.6 N ± 12.1 N; and EG IV 30.3 N ± 7.8 N. There were statistically significant differences between the control group and the experimental groups and also between experimental group IV and the other experimental groups (II and III). Radiographs showed callus formation in all the fractured groups, thus indicating that they had undergone the normal tissue repair process. Conclusion: EG IV, which underwent laser therapy with a dosage of 15 J/cm(2), showed the highest maximum force value (N) among the experimental groups, thus demonstrating the influence of higher laser dosage on bone repair.
format Online
Article
Text
id pubmed-4799407
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-47994072016-04-01 EFFECT OF LOW-LEVEL LASER (GAAS, 904HM) FOR BONE REPAIR ON FRACTURES IN RATS Léo, Jorge Alfredo Cunha, Alessanda da de Oliveira, Elias Félix Prado, Reuder Pereira Rev Bras Ortop Original Article Objective: To analyze the effects of low-level laser therapy (GaAs, 904 nm) for bone repair on tibial fractures in rats. Methods: Forty rats were divided into four groups of 10 animals: control group without fracture (CG); fracture group without treatment (EG II); fracture group treated with laser at 10 J/cm(2) (EG III); and fracture group treated with laser at 15 J/cm2 (EG IV). The fracture was produced surgically and the treatment lasted 45 days, done on alternate days. After treatment completion, the rats were sacrificed. The tibias were radiographed and subjected to mechanical three-point flexion tests in order to evaluate the maximum force (N) required to break them. Results: The observed maximum force values (N) were: control group (CG) of 51.5 N ± 7.9 N; EG II 17.2 N ± 7.8 N; EG III 16.6 N ± 12.1 N; and EG IV 30.3 N ± 7.8 N. There were statistically significant differences between the control group and the experimental groups and also between experimental group IV and the other experimental groups (II and III). Radiographs showed callus formation in all the fractured groups, thus indicating that they had undergone the normal tissue repair process. Conclusion: EG IV, which underwent laser therapy with a dosage of 15 J/cm(2), showed the highest maximum force value (N) among the experimental groups, thus demonstrating the influence of higher laser dosage on bone repair. Elsevier 2015-12-06 /pmc/articles/PMC4799407/ /pubmed/27042627 http://dx.doi.org/10.1016/S2255-4971(15)30092-6 Text en © 2012 Sociedade Brasileira de Ortopedia e Traumatologia http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Léo, Jorge Alfredo
Cunha, Alessanda da
de Oliveira, Elias Félix
Prado, Reuder Pereira
EFFECT OF LOW-LEVEL LASER (GAAS, 904HM) FOR BONE REPAIR ON FRACTURES IN RATS
title EFFECT OF LOW-LEVEL LASER (GAAS, 904HM) FOR BONE REPAIR ON FRACTURES IN RATS
title_full EFFECT OF LOW-LEVEL LASER (GAAS, 904HM) FOR BONE REPAIR ON FRACTURES IN RATS
title_fullStr EFFECT OF LOW-LEVEL LASER (GAAS, 904HM) FOR BONE REPAIR ON FRACTURES IN RATS
title_full_unstemmed EFFECT OF LOW-LEVEL LASER (GAAS, 904HM) FOR BONE REPAIR ON FRACTURES IN RATS
title_short EFFECT OF LOW-LEVEL LASER (GAAS, 904HM) FOR BONE REPAIR ON FRACTURES IN RATS
title_sort effect of low-level laser (gaas, 904hm) for bone repair on fractures in rats
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4799407/
https://www.ncbi.nlm.nih.gov/pubmed/27042627
http://dx.doi.org/10.1016/S2255-4971(15)30092-6
work_keys_str_mv AT leojorgealfredo effectoflowlevellasergaas904hmforbonerepaironfracturesinrats
AT cunhaalessandada effectoflowlevellasergaas904hmforbonerepaironfracturesinrats
AT deoliveiraeliasfelix effectoflowlevellasergaas904hmforbonerepaironfracturesinrats
AT pradoreuderpereira effectoflowlevellasergaas904hmforbonerepaironfracturesinrats