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EFFECT OF LOW-LEVEL LASER (GAAS, 904HM) FOR BONE REPAIR ON FRACTURES IN RATS
Objective: To analyze the effects of low-level laser therapy (GaAs, 904 nm) for bone repair on tibial fractures in rats. Methods: Forty rats were divided into four groups of 10 animals: control group without fracture (CG); fracture group without treatment (EG II); fracture group treated with laser a...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4799407/ https://www.ncbi.nlm.nih.gov/pubmed/27042627 http://dx.doi.org/10.1016/S2255-4971(15)30092-6 |
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author | Léo, Jorge Alfredo Cunha, Alessanda da de Oliveira, Elias Félix Prado, Reuder Pereira |
author_facet | Léo, Jorge Alfredo Cunha, Alessanda da de Oliveira, Elias Félix Prado, Reuder Pereira |
author_sort | Léo, Jorge Alfredo |
collection | PubMed |
description | Objective: To analyze the effects of low-level laser therapy (GaAs, 904 nm) for bone repair on tibial fractures in rats. Methods: Forty rats were divided into four groups of 10 animals: control group without fracture (CG); fracture group without treatment (EG II); fracture group treated with laser at 10 J/cm(2) (EG III); and fracture group treated with laser at 15 J/cm2 (EG IV). The fracture was produced surgically and the treatment lasted 45 days, done on alternate days. After treatment completion, the rats were sacrificed. The tibias were radiographed and subjected to mechanical three-point flexion tests in order to evaluate the maximum force (N) required to break them. Results: The observed maximum force values (N) were: control group (CG) of 51.5 N ± 7.9 N; EG II 17.2 N ± 7.8 N; EG III 16.6 N ± 12.1 N; and EG IV 30.3 N ± 7.8 N. There were statistically significant differences between the control group and the experimental groups and also between experimental group IV and the other experimental groups (II and III). Radiographs showed callus formation in all the fractured groups, thus indicating that they had undergone the normal tissue repair process. Conclusion: EG IV, which underwent laser therapy with a dosage of 15 J/cm(2), showed the highest maximum force value (N) among the experimental groups, thus demonstrating the influence of higher laser dosage on bone repair. |
format | Online Article Text |
id | pubmed-4799407 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-47994072016-04-01 EFFECT OF LOW-LEVEL LASER (GAAS, 904HM) FOR BONE REPAIR ON FRACTURES IN RATS Léo, Jorge Alfredo Cunha, Alessanda da de Oliveira, Elias Félix Prado, Reuder Pereira Rev Bras Ortop Original Article Objective: To analyze the effects of low-level laser therapy (GaAs, 904 nm) for bone repair on tibial fractures in rats. Methods: Forty rats were divided into four groups of 10 animals: control group without fracture (CG); fracture group without treatment (EG II); fracture group treated with laser at 10 J/cm(2) (EG III); and fracture group treated with laser at 15 J/cm2 (EG IV). The fracture was produced surgically and the treatment lasted 45 days, done on alternate days. After treatment completion, the rats were sacrificed. The tibias were radiographed and subjected to mechanical three-point flexion tests in order to evaluate the maximum force (N) required to break them. Results: The observed maximum force values (N) were: control group (CG) of 51.5 N ± 7.9 N; EG II 17.2 N ± 7.8 N; EG III 16.6 N ± 12.1 N; and EG IV 30.3 N ± 7.8 N. There were statistically significant differences between the control group and the experimental groups and also between experimental group IV and the other experimental groups (II and III). Radiographs showed callus formation in all the fractured groups, thus indicating that they had undergone the normal tissue repair process. Conclusion: EG IV, which underwent laser therapy with a dosage of 15 J/cm(2), showed the highest maximum force value (N) among the experimental groups, thus demonstrating the influence of higher laser dosage on bone repair. Elsevier 2015-12-06 /pmc/articles/PMC4799407/ /pubmed/27042627 http://dx.doi.org/10.1016/S2255-4971(15)30092-6 Text en © 2012 Sociedade Brasileira de Ortopedia e Traumatologia http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Original Article Léo, Jorge Alfredo Cunha, Alessanda da de Oliveira, Elias Félix Prado, Reuder Pereira EFFECT OF LOW-LEVEL LASER (GAAS, 904HM) FOR BONE REPAIR ON FRACTURES IN RATS |
title | EFFECT OF LOW-LEVEL LASER (GAAS, 904HM) FOR BONE REPAIR ON FRACTURES IN RATS |
title_full | EFFECT OF LOW-LEVEL LASER (GAAS, 904HM) FOR BONE REPAIR ON FRACTURES IN RATS |
title_fullStr | EFFECT OF LOW-LEVEL LASER (GAAS, 904HM) FOR BONE REPAIR ON FRACTURES IN RATS |
title_full_unstemmed | EFFECT OF LOW-LEVEL LASER (GAAS, 904HM) FOR BONE REPAIR ON FRACTURES IN RATS |
title_short | EFFECT OF LOW-LEVEL LASER (GAAS, 904HM) FOR BONE REPAIR ON FRACTURES IN RATS |
title_sort | effect of low-level laser (gaas, 904hm) for bone repair on fractures in rats |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4799407/ https://www.ncbi.nlm.nih.gov/pubmed/27042627 http://dx.doi.org/10.1016/S2255-4971(15)30092-6 |
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