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T Helper 1 and T Helper 2 Cytokines Differentially Modulate Expression of Filaggrin and its Processing Proteases in Human Keratinocytes

BACKGROUND: Atopic dermatitis (AD) is characterized by defective skin barrier and imbalance in T helper 1/T helper 2 (Th1/Th2) cytokine expression. Filaggrin (FLG) is the key protein to maintaining skin barrier function. Recent studies indicated that Th1/Th2 cytokines influence FLG expression in ker...

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Detalles Bibliográficos
Autores principales:	Di, Zheng-Hong, Ma, Lei, Qi, Rui-Qun, Sun, Xiao-Dong, Huo, Wei, Zhang, Li, Lyu, Ya-Ni, Hong, Yu-Xiao, Chen, Hong-Duo, Gao, Xing-Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4799573/ https://www.ncbi.nlm.nih.gov/pubmed/26831231 http://dx.doi.org/10.4103/0366-6999.174489

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