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Inhibiting HMGB1 with Glycyrrhizic Acid Protects Brain Injury after DAI via Its Anti-Inflammatory Effect

High-mobility group box 1 (HMGB1), a nuclear protein that has endogenous cytokine-like activity, is involved in several neurological diseases by mediating inflammatory response. In this study, a lateral head rotation device was used to establish a rat diffuse axonal injury (DAI) model. The dynamic e...

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Detalles Bibliográficos
Autores principales: Pang, Honggang, Huang, Tinqin, Song, Jinning, Li, Dandong, Zhao, Yonglin, Ma, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4799817/
https://www.ncbi.nlm.nih.gov/pubmed/27041825
http://dx.doi.org/10.1155/2016/4569521

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