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Normal Performance of Fmr1 Mice on a Touchscreen Delayed Nonmatching to Position Working Memory Task123

Fragile X syndrome is a neurodevelopmental disorder characterized by mild-to-severe cognitive deficits. The complete absence of Fmr1 and its protein product in the mouse model of fragile X (Fmr1 KO) provides construct validity. A major conundrum in the field is the remarkably normal performance of F...

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Detalles Bibliográficos
Autores principales: Leach, Prescott T., Hayes, Jane, Pride, Michael, Silverman, Jill L., Crawley, Jacqueline N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800045/
https://www.ncbi.nlm.nih.gov/pubmed/27022628
http://dx.doi.org/10.1523/ENEURO.0143-15.2016