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Recording and treatment of premenstrual syndrome in UK general practice: a retrospective cohort study
OBJECTIVES: To investigate the rate of recording of premenstrual syndrome diagnoses in UK primary care and describe pharmacological treatments initiated following a premenstrual syndrome (PMS) diagnosis. DESIGN: Retrospective cohort study. SETTING: UK primary care. PARTICIPANTS: Women registered wit...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800111/ https://www.ncbi.nlm.nih.gov/pubmed/26993623 http://dx.doi.org/10.1136/bmjopen-2015-010244 |
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author | Sammon, Cormac J Nazareth, Irwin Petersen, Irene |
author_facet | Sammon, Cormac J Nazareth, Irwin Petersen, Irene |
author_sort | Sammon, Cormac J |
collection | PubMed |
description | OBJECTIVES: To investigate the rate of recording of premenstrual syndrome diagnoses in UK primary care and describe pharmacological treatments initiated following a premenstrual syndrome (PMS) diagnosis. DESIGN: Retrospective cohort study. SETTING: UK primary care. PARTICIPANTS: Women registered with a practice contributing to The Health Improvement Network primary care database between 1995 and 2013. PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome was the rate of first premenstrual syndrome records per 1000 person years, stratified by calendar year and age. The secondary outcome was the proportions of women with a premenstrual syndrome record prescribed a selective serotonin reuptake inhibitor, progestogen, oestrogen, combined oral contraceptive, progestin only contraceptive, gonadotrophin-releasing hormone, danazol and vitamin B(6). RESULTS: The rate of recording of premenstrual syndrome diagnoses decreased over calendar time from 8.43 in 1995 to 1.72 in 2013. Of the 38 614 women without treatment in the 6 months prior to diagnosis, 54% received a potentially premenstrual syndrome-related prescription on the day of their first PMS record while 77% received a prescription in the 24 months after. Between 1995 and 1999, the majority of women were prescribed progestogens (23%) or vitamin B(6) (20%) on the day of their first PMS record; after 1999, these figures fell to 3% for progestogen and vitamin B(6) with the majority of women instead being prescribed a selective serotonin reuptake inhibitor (28%) or combined oral contraceptive (17%). CONCLUSIONS: Recording of premenstrual syndrome diagnoses in UK primary care has declined substantially over time and preferred prescription treatment has changed from progestogen to selective serotonin reuptake inhibitor and combined oral contraceptives. |
format | Online Article Text |
id | pubmed-4800111 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-48001112016-03-29 Recording and treatment of premenstrual syndrome in UK general practice: a retrospective cohort study Sammon, Cormac J Nazareth, Irwin Petersen, Irene BMJ Open Reproductive Medicine OBJECTIVES: To investigate the rate of recording of premenstrual syndrome diagnoses in UK primary care and describe pharmacological treatments initiated following a premenstrual syndrome (PMS) diagnosis. DESIGN: Retrospective cohort study. SETTING: UK primary care. PARTICIPANTS: Women registered with a practice contributing to The Health Improvement Network primary care database between 1995 and 2013. PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome was the rate of first premenstrual syndrome records per 1000 person years, stratified by calendar year and age. The secondary outcome was the proportions of women with a premenstrual syndrome record prescribed a selective serotonin reuptake inhibitor, progestogen, oestrogen, combined oral contraceptive, progestin only contraceptive, gonadotrophin-releasing hormone, danazol and vitamin B(6). RESULTS: The rate of recording of premenstrual syndrome diagnoses decreased over calendar time from 8.43 in 1995 to 1.72 in 2013. Of the 38 614 women without treatment in the 6 months prior to diagnosis, 54% received a potentially premenstrual syndrome-related prescription on the day of their first PMS record while 77% received a prescription in the 24 months after. Between 1995 and 1999, the majority of women were prescribed progestogens (23%) or vitamin B(6) (20%) on the day of their first PMS record; after 1999, these figures fell to 3% for progestogen and vitamin B(6) with the majority of women instead being prescribed a selective serotonin reuptake inhibitor (28%) or combined oral contraceptive (17%). CONCLUSIONS: Recording of premenstrual syndrome diagnoses in UK primary care has declined substantially over time and preferred prescription treatment has changed from progestogen to selective serotonin reuptake inhibitor and combined oral contraceptives. BMJ Publishing Group 2016-03-18 /pmc/articles/PMC4800111/ /pubmed/26993623 http://dx.doi.org/10.1136/bmjopen-2015-010244 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/ This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
spellingShingle | Reproductive Medicine Sammon, Cormac J Nazareth, Irwin Petersen, Irene Recording and treatment of premenstrual syndrome in UK general practice: a retrospective cohort study |
title | Recording and treatment of premenstrual syndrome in UK general practice: a retrospective cohort study |
title_full | Recording and treatment of premenstrual syndrome in UK general practice: a retrospective cohort study |
title_fullStr | Recording and treatment of premenstrual syndrome in UK general practice: a retrospective cohort study |
title_full_unstemmed | Recording and treatment of premenstrual syndrome in UK general practice: a retrospective cohort study |
title_short | Recording and treatment of premenstrual syndrome in UK general practice: a retrospective cohort study |
title_sort | recording and treatment of premenstrual syndrome in uk general practice: a retrospective cohort study |
topic | Reproductive Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800111/ https://www.ncbi.nlm.nih.gov/pubmed/26993623 http://dx.doi.org/10.1136/bmjopen-2015-010244 |
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