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Dual Acting Neuraminidase Inhibitors Open New Opportunities to Disrupt the Lethal Synergism between Streptococcus pneumoniae and Influenza Virus
Secondary infections with Streptococcus pneumoniae cause severe pneumonia and enhance lethality during influenza epidemics and pandemics. Structural and functional similarities with viral neuraminidase (NA) suggest that the highly prevalent pneumococcal NAs, NanA and NanB, might contribute to this l...
Autores principales: | Walther, Elisabeth, Xu, Zhongli, Richter, Martina, Kirchmair, Johannes, Grienke, Ulrike, Rollinger, Judith M., Krumbholz, Andi, Saluz, Hans P., Pfister, Wolfgang, Sauerbrei, Andreas, Schmidtke, Michaela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800182/ https://www.ncbi.nlm.nih.gov/pubmed/27047471 http://dx.doi.org/10.3389/fmicb.2016.00357 |
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