Par6G suppresses cell proliferation and is targeted by loss-of-function mutations in multiple cancers

Differentiated epithelial structure communicates with individual constituent epithelial cells to suppress their proliferation activity. However, the pathways linking epithelial structure to cessation of the cell proliferation machinery or to unscheduled proliferation in the context of tumorigenesis...

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Detalles Bibliográficos
Autores principales: Marques, E, Englund, J I, Tervonen, T A, Virkunen, E, Laakso, M, Myllynen, M, Mäkelä, A, Ahvenainen, M, Lepikhova, T, Monni, O, Hautaniemi, S, Klefström, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800288/
https://www.ncbi.nlm.nih.gov/pubmed/26073086
http://dx.doi.org/10.1038/onc.2015.196

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