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Clinical impact of mutation fraction in epidermal growth factor receptor mutation positive NSCLC patients

BACKGROUND: We examined clinical outcomes in a population-based cohort of EGFR mutant advanced NSCLC patients, exploring the potential role of factors including tumour EGFR mutation fraction and cellularity in predicting outcomes. METHODS: A cohort of patients with EGFR mutant advanced NSCLC was ide...

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Detalles Bibliográficos
Autores principales: Martin, Petra, Shiau, Carolyn J, Pasic, Maria, Tsao, Ming, Kamel-Reid, Suzanne, Lin, Stephanie, Tudor, Roxana, Cheng, Susanna, Higgins, Brian, Burkes, Ronald, Ng, Matilda, Arif, Saroosh, Ellis, Peter M, Hubay, Stacy, Kuruvilla, Sara, Laurie, Scott A, Li, Jing, Hwang, David, Lau, Anthea, Shepherd, Frances A, Le, Lisa W, Leighl, Natasha B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800294/
https://www.ncbi.nlm.nih.gov/pubmed/26889973
http://dx.doi.org/10.1038/bjc.2016.22