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Single-cell RNA-seq reveals activation of unique gene groups as a consequence of stem cell-parenchymal cell fusion

Fusion of donor mesenchymal stem cells with parenchymal cells of the recipient can occur in the brain, liver, intestine and heart following transplantation. The therapeutic benefit or detriment of resultant hybrids is unknown. Here we sought a global view of phenotypic diversification of mesenchymal...

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Detalles Bibliográficos
Autores principales: Freeman, Brian T., Jung, Jangwook P., Ogle, Brenda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800419/
https://www.ncbi.nlm.nih.gov/pubmed/26997336
http://dx.doi.org/10.1038/srep23270