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CpG methylation patterns of human mitochondrial DNA

The epigenetic modification of mitochondrial DNA (mtDNA) is still in controversy. To clarify this point, we applied the gold standard method for DNA methylation, bisulfite pyrosequencing, to examine human mtDNA methylation status. Before bisulfite conversion, BamHI was used to digest DNA to open the...

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Detalles Bibliográficos
Autores principales: Liu, Baojing, Du, Qingqing, Chen, Lu, Fu, Guangping, Li, Shujin, Fu, Lihong, Zhang, Xiaojing, Ma, Chunling, Bin, Cong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800444/
https://www.ncbi.nlm.nih.gov/pubmed/26996456
http://dx.doi.org/10.1038/srep23421

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