Minocycline as a re-purposed anti-Wolbachia macrofilaricide: superiority compared with doxycycline regimens in a murine infection model of human lymphatic filariasis

Lymphatic filariasis and onchocerciasis are parasitic helminth diseases, which cause severe morbidities such as elephantiasis, skin disease and blindness, presenting a major public health burden in endemic communities. The anti-Wolbachia consortium (A·WOL: http://www.a-wol.com/) has identified a num...

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Detalles Bibliográficos
Autores principales: Sharma, Raman, Jayoussi, Ghaith Al, Tyrer, Hayley E., Gamble, Joanne, Hayward, Laura, Guimaraes, Ana F., Davies, Jill, Waterhouse, David, Cook, Darren A. N., Myhill, Laura J., Clare, Rachel H., Cassidy, Andrew, Steven, Andrew, Johnston, Kelly L., Ford, Louise, Turner, Joseph D., Ward, Stephen A., Taylor, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800446/
https://www.ncbi.nlm.nih.gov/pubmed/26996237
http://dx.doi.org/10.1038/srep23458

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