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A Critical Reappraisal of Prolonged Neutropenia as a Risk Factor for Invasive Pulmonary Aspergillosis

Prolonged neutropenia is generally thought to be the major factor for invasive pulmonary aspergillosis (IPA). In the present study, we characterize the frequency, severity, and duration of neutropenia that immediately precedes IPA. Prolonged neutropenia was identified in only one third of all IPA ca...

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Autores principales: Abers, Michael S., Ghebremichael, Musie S., Timmons, Allison K., Warren, H. Shaw, Poznansky, Mark C., Vyas, Jatin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800458/
https://www.ncbi.nlm.nih.gov/pubmed/27006961
http://dx.doi.org/10.1093/ofid/ofw036
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author Abers, Michael S.
Ghebremichael, Musie S.
Timmons, Allison K.
Warren, H. Shaw
Poznansky, Mark C.
Vyas, Jatin M.
author_facet Abers, Michael S.
Ghebremichael, Musie S.
Timmons, Allison K.
Warren, H. Shaw
Poznansky, Mark C.
Vyas, Jatin M.
author_sort Abers, Michael S.
collection PubMed
description Prolonged neutropenia is generally thought to be the major factor for invasive pulmonary aspergillosis (IPA). In the present study, we characterize the frequency, severity, and duration of neutropenia that immediately precedes IPA. Prolonged neutropenia was identified in only one third of all IPA cases and occurred exclusively in hematologic patients.
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spelling pubmed-48004582016-03-22 A Critical Reappraisal of Prolonged Neutropenia as a Risk Factor for Invasive Pulmonary Aspergillosis Abers, Michael S. Ghebremichael, Musie S. Timmons, Allison K. Warren, H. Shaw Poznansky, Mark C. Vyas, Jatin M. Open Forum Infect Dis Brief Reports Prolonged neutropenia is generally thought to be the major factor for invasive pulmonary aspergillosis (IPA). In the present study, we characterize the frequency, severity, and duration of neutropenia that immediately precedes IPA. Prolonged neutropenia was identified in only one third of all IPA cases and occurred exclusively in hematologic patients. Oxford University Press 2016-02-12 /pmc/articles/PMC4800458/ /pubmed/27006961 http://dx.doi.org/10.1093/ofid/ofw036 Text en © The Author 2016. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com.
spellingShingle Brief Reports
Abers, Michael S.
Ghebremichael, Musie S.
Timmons, Allison K.
Warren, H. Shaw
Poznansky, Mark C.
Vyas, Jatin M.
A Critical Reappraisal of Prolonged Neutropenia as a Risk Factor for Invasive Pulmonary Aspergillosis
title A Critical Reappraisal of Prolonged Neutropenia as a Risk Factor for Invasive Pulmonary Aspergillosis
title_full A Critical Reappraisal of Prolonged Neutropenia as a Risk Factor for Invasive Pulmonary Aspergillosis
title_fullStr A Critical Reappraisal of Prolonged Neutropenia as a Risk Factor for Invasive Pulmonary Aspergillosis
title_full_unstemmed A Critical Reappraisal of Prolonged Neutropenia as a Risk Factor for Invasive Pulmonary Aspergillosis
title_short A Critical Reappraisal of Prolonged Neutropenia as a Risk Factor for Invasive Pulmonary Aspergillosis
title_sort critical reappraisal of prolonged neutropenia as a risk factor for invasive pulmonary aspergillosis
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800458/
https://www.ncbi.nlm.nih.gov/pubmed/27006961
http://dx.doi.org/10.1093/ofid/ofw036
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