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An Automated Microscale Thermophoresis Screening Approach for Fragment-Based Lead Discovery
Fragment-based lead discovery has proved to be an effective alternative to high-throughput screenings in identifying chemical matter that can be developed into robust lead compounds. The search for optimal combinations of biophysical techniques that can correctly and efficiently identify and quantif...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800460/ https://www.ncbi.nlm.nih.gov/pubmed/26637553 http://dx.doi.org/10.1177/1087057115618347 |