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An Automated Microscale Thermophoresis Screening Approach for Fragment-Based Lead Discovery
Fragment-based lead discovery has proved to be an effective alternative to high-throughput screenings in identifying chemical matter that can be developed into robust lead compounds. The search for optimal combinations of biophysical techniques that can correctly and efficiently identify and quantif...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
SAGE Publications
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800460/ https://www.ncbi.nlm.nih.gov/pubmed/26637553 http://dx.doi.org/10.1177/1087057115618347 |