Cargando…
Alterations to mTORC1 signaling in the skeletal muscle differentially affect whole-body metabolism
BACKGROUND: The mammalian target of rapamycin complex 1 (mTORC1) is a central node in a network of signaling pathways controlling cell growth and survival. This multiprotein complex integrates external signals and affects different nutrient pathways in various organs. However, it is not clear how al...
Autores principales: | Guridi, Maitea, Kupr, Barbara, Romanino, Klaas, Lin, Shuo, Falcetta, Denis, Tintignac, Lionel, Rüegg, Markus A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800774/ https://www.ncbi.nlm.nih.gov/pubmed/27004103 http://dx.doi.org/10.1186/s13395-016-0084-8 |
Ejemplares similares
-
Differential response of skeletal muscles to mTORC1 signaling during atrophy and hypertrophy
por: Bentzinger, C Florian, et al.
Publicado: (2013) -
mTORC1 and PKB/Akt control the muscle response to denervation by regulating autophagy and HDAC4
por: Castets, Perrine, et al.
Publicado: (2019) -
The neuromuscular junction is a focal point of mTORC1 signaling in sarcopenia
por: Ham, Daniel J., et al.
Publicado: (2020) -
mTORC1 signalling is not essential for the maintenance of muscle mass and function in adult sedentary mice
por: Ham, Alexander S., et al.
Publicado: (2019) -
Dual roles of mTORC1-dependent activation of the ubiquitin-proteasome system in muscle proteostasis
por: Kaiser, Marco S., et al.
Publicado: (2022)