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Vitamin D supplementation decreases Aspergillus fumigatus specific Th2 responses in CF patients with aspergillus sensitization: a phase one open-label study
BACKGROUND: Patients with cystic fibrosis (CF) complicated by allergic bronchopulmonary aspergillosis (ABPA) are vitamin D deficient and in vitro treatment with 1,25 (OH)(2) vitamin D(3) of CD4+ cells from CF patients with ABPA decreases Aspergillus fumigatus(Af)-induced Th2 responses. This Phase I...
Autores principales: | Nguyen, Nikki Lynn Hue, Pilewski, Joseph M., Celedón, Juan C., Mandalapu, Sivanarayana, Blanchard, Megan L., DeRicco, Adrienne, Hartigan, Elizabeth, Alcorn, John F., Kolls, Jay K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801182/ https://www.ncbi.nlm.nih.gov/pubmed/27011794 http://dx.doi.org/10.1186/s40733-015-0003-5 |
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