One-step self-assembled nanomicelles for improving the oral bioavailability of nimodipine

Our study aimed to develop a self-assembled nanomicelle for oral administration of nimodipine (NIM) with poor water solubility. Using Solutol(®) HS15, the NIM-loaded self-assembled nanomicelles displayed a near-spherical morphology with a narrow size distribution of 12.57±0.21 nm (polydispersity ind...

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Detalles Bibliográficos
Autores principales: Luo, Jing-Wen, Zhang, Zhi-Rong, Gong, Tao, Fu, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801194/
https://www.ncbi.nlm.nih.gov/pubmed/27042060
http://dx.doi.org/10.2147/IJN.S97834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801194/
https://www.ncbi.nlm.nih.gov/pubmed/27042060
http://dx.doi.org/10.2147/IJN.S97834

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