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One-step self-assembled nanomicelles for improving the oral bioavailability of nimodipine
Our study aimed to develop a self-assembled nanomicelle for oral administration of nimodipine (NIM) with poor water solubility. Using Solutol(®) HS15, the NIM-loaded self-assembled nanomicelles displayed a near-spherical morphology with a narrow size distribution of 12.57±0.21 nm (polydispersity ind...
Autores principales: | Luo, Jing-Wen, Zhang, Zhi-Rong, Gong, Tao, Fu, Yao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801194/ https://www.ncbi.nlm.nih.gov/pubmed/27042060 http://dx.doi.org/10.2147/IJN.S97834 |
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