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miR-410 and miR-495 Are Dynamically Regulated in Diverse Cardiomyopathies and Their Inhibition Attenuates Pathological Hypertrophy
Noncoding RNAs have emerged as important modulators in cardiac development and pathological remodeling. Recently, we demonstrated that regulation of the Gtl2-Dio3 noncoding RNA locus is dependent on the MEF2 transcription factor in cardiac muscle, and that two of its encoded miRNAs, miR-410 and miR-...
Autores principales: | Clark, Amanda L., Maruyama, Sonomi, Sano, Soichi, Accorsi, Anthony, Girgenrath, Mahasweta, Walsh, Kenneth, Naya, Francisco J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801331/ https://www.ncbi.nlm.nih.gov/pubmed/26999812 http://dx.doi.org/10.1371/journal.pone.0151515 |
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