Impact of a CXCL12/CXCR4 Antagonist in Bleomycin (BLM) Induced Pulmonary Fibrosis and Carbon Tetrachloride (CCl4) Induced Hepatic Fibrosis in Mice

Modulation of chemokine CXCL12 and its receptor CXCR4 has been implicated in attenuation of bleomycin (BLM)-induced pulmonary fibrosis and carbon tetrachloride (CCl(4))-induced hepatic injury. In pulmonary fibrosis, published reports suggest that collagen production in the injured lung is derived fr...

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Detalles Bibliográficos
Autores principales: Chow, Leola N., Schreiner, Petra, Ng, Betina Y. Y., Lo, Bernard, Hughes, Michael R., Scott, R. Wilder, Gusti, Vionarica, Lecour, Samantha, Simonson, Eric, Manisali, Irina, Barta, Ingrid, McNagny, Kelly M., Crawford, Jason, Webb, Murray, Underhill, T. Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801399/
https://www.ncbi.nlm.nih.gov/pubmed/26998906
http://dx.doi.org/10.1371/journal.pone.0151765

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