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Novel Methodology for Rapid Detection of KRAS Mutation Using PNA-LNA Mediated Loop-Mediated Isothermal Amplification
Detecting point mutation of human cancer cells quickly and accurately is gaining in importance for pathological diagnosis and choice of therapeutic approach. In the present study, we present novel methodology, peptide nucleic acid—locked nucleic acid mediated loop-mediated isothermal amplification (...
Autores principales: | Itonaga, Masahiro, Matsuzaki, Ibu, Warigaya, Kenji, Tamura, Takaaki, Shimizu, Yuki, Fujimoto, Masakazu, Kojima, Fumiyoshi, Ichinose, Masao, Murata, Shin-ichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801409/ https://www.ncbi.nlm.nih.gov/pubmed/26999437 http://dx.doi.org/10.1371/journal.pone.0151654 |
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