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Irradiation of necrotic cancer cells, employed for pulsing dendritic cells (DCs), potentiates DC vaccine-induced antitumor immunity against high-grade glioma
Dendritic cell (DC)-based immunotherapy has yielded promising results against high-grade glioma (HGG). However, the efficacy of DC vaccines is abated by HGG-induced immunosuppression and lack of attention toward the immunogenicity of the tumor lysate/cells used for pulsing DCs. A literature analysis...
Autores principales: | Vandenberk, Lien, Garg, Abhishek D., Verschuere, Tina, Koks, Carolien, Belmans, Jochen, Beullens, Monique, Agostinis, Patrizia, De Vleeschouwer, Steven, Van Gool, Stefaan W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801426/ https://www.ncbi.nlm.nih.gov/pubmed/27057467 http://dx.doi.org/10.1080/2162402X.2015.1083669 |
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