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Investigation of the interactions between Pt(II) and Pd(II) derivatives of 5,10,15,20-tetrakis (N-methyl-4-pyridyl) porphyrin and G-quadruplex DNA

ABSTRACT: G-quadruplexes are non-canonical DNA structures formed by guanine-rich DNA sequences that are implicated in cancer and aging. Understanding how small molecule ligands interact with quadruplexes is essential both to the development of novel anticancer therapeutics and to the design of new q...

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Detalles Bibliográficos
Autores principales:	Sabharwal, Navin C., Mendoza, Oscar, Nicoludis, John M., Ruan, Thomas, Mergny, Jean-Louis, Yatsunyk, Liliya A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2016
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801998/ https://www.ncbi.nlm.nih.gov/pubmed/26748794 http://dx.doi.org/10.1007/s00775-015-1325-8

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