Coagulation induced by C3aR-dependent NETosis drives protumorigenic neutrophils during small intestinal tumorigenesis

Excessive activation of blood coagulation and neutrophil accumulation have been described in several human cancers. However, whether hypercoagulation and neutrophilia are linked and involved in cancer development is currently unknown. Here we show that spontaneous intestinal tumorigenesis correlates...

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Detalles Bibliográficos
Autores principales: Guglietta, Silvia, Chiavelli, Andrea, Zagato, Elena, Krieg, Carsten, Gandini, Sara, Ravenda, Paola Simona, Bazolli, Barbara, Lu, Bao, Penna, Giuseppe, Rescigno, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802169/
https://www.ncbi.nlm.nih.gov/pubmed/26996437
http://dx.doi.org/10.1038/ncomms11037

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