A rare case of true carcinosarcoma of the breast

BACKGROUND: True carcinosarcoma of the breast is an extremely rare condition, accounting for 0.08–0.2% of all breast malignancies. The correct definition of this tumor requires both a carcinomatous component and a malignant non-epithelial component of mesenchymal origin, without evidence of a transi...

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Detalles Bibliográficos
Autores principales: Accurso, Antonello, Ciancia, Giuseppe, Della Corte, Gianni Antonio, Reale, Paola, Accardo, Giuseppe, Salerno, Carmela, Bordoni, Daniele, Falco, Giuseppe, Rocco, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802189/
https://www.ncbi.nlm.nih.gov/pubmed/26978126
http://dx.doi.org/10.1016/j.ijscr.2016.03.004
Descripción
Sumario:BACKGROUND: True carcinosarcoma of the breast is an extremely rare condition, accounting for 0.08–0.2% of all breast malignancies. The correct definition of this tumor requires both a carcinomatous component and a malignant non-epithelial component of mesenchymal origin, without evidence of a transition zone between the two elements. CASE PRESENTATION: We present a case of a 49-year-old woman presenting with a 4 cm mass at the level of her left breast upper-outer quadrant with a histologic diagnosis of true carcinosarcoma of the breast. DISCUSSION: The most appropriate therapeutic regimens for breast carcinosarcoma are still unclear because of the rarity of this condition, but Breast Conserving Treatment (BCT) followed by adjuvant chemotherapy seems to provide a prognosis equalling that of usual Invasive Ductal Carcinoma of the breast.

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