A rare case of true carcinosarcoma of the breast

BACKGROUND: True carcinosarcoma of the breast is an extremely rare condition, accounting for 0.08–0.2% of all breast malignancies. The correct definition of this tumor requires both a carcinomatous component and a malignant non-epithelial component of mesenchymal origin, without evidence of a transi...

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Autores principales: Accurso, Antonello, Ciancia, Giuseppe, Della Corte, Gianni Antonio, Reale, Paola, Accardo, Giuseppe, Salerno, Carmela, Bordoni, Daniele, Falco, Giuseppe, Rocco, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802189/
https://www.ncbi.nlm.nih.gov/pubmed/26978126
http://dx.doi.org/10.1016/j.ijscr.2016.03.004
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author Accurso, Antonello
Ciancia, Giuseppe
Della Corte, Gianni Antonio
Reale, Paola
Accardo, Giuseppe
Salerno, Carmela
Bordoni, Daniele
Falco, Giuseppe
Rocco, Nicola
author_facet Accurso, Antonello
Ciancia, Giuseppe
Della Corte, Gianni Antonio
Reale, Paola
Accardo, Giuseppe
Salerno, Carmela
Bordoni, Daniele
Falco, Giuseppe
Rocco, Nicola
author_sort Accurso, Antonello
collection PubMed
description BACKGROUND: True carcinosarcoma of the breast is an extremely rare condition, accounting for 0.08–0.2% of all breast malignancies. The correct definition of this tumor requires both a carcinomatous component and a malignant non-epithelial component of mesenchymal origin, without evidence of a transition zone between the two elements. CASE PRESENTATION: We present a case of a 49-year-old woman presenting with a 4 cm mass at the level of her left breast upper-outer quadrant with a histologic diagnosis of true carcinosarcoma of the breast. DISCUSSION: The most appropriate therapeutic regimens for breast carcinosarcoma are still unclear because of the rarity of this condition, but Breast Conserving Treatment (BCT) followed by adjuvant chemotherapy seems to provide a prognosis equalling that of usual Invasive Ductal Carcinoma of the breast.
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spelling pubmed-48021892016-04-06 A rare case of true carcinosarcoma of the breast Accurso, Antonello Ciancia, Giuseppe Della Corte, Gianni Antonio Reale, Paola Accardo, Giuseppe Salerno, Carmela Bordoni, Daniele Falco, Giuseppe Rocco, Nicola Int J Surg Case Rep Case Report BACKGROUND: True carcinosarcoma of the breast is an extremely rare condition, accounting for 0.08–0.2% of all breast malignancies. The correct definition of this tumor requires both a carcinomatous component and a malignant non-epithelial component of mesenchymal origin, without evidence of a transition zone between the two elements. CASE PRESENTATION: We present a case of a 49-year-old woman presenting with a 4 cm mass at the level of her left breast upper-outer quadrant with a histologic diagnosis of true carcinosarcoma of the breast. DISCUSSION: The most appropriate therapeutic regimens for breast carcinosarcoma are still unclear because of the rarity of this condition, but Breast Conserving Treatment (BCT) followed by adjuvant chemotherapy seems to provide a prognosis equalling that of usual Invasive Ductal Carcinoma of the breast. Elsevier 2016-03-10 /pmc/articles/PMC4802189/ /pubmed/26978126 http://dx.doi.org/10.1016/j.ijscr.2016.03.004 Text en © 2016 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Accurso, Antonello
Ciancia, Giuseppe
Della Corte, Gianni Antonio
Reale, Paola
Accardo, Giuseppe
Salerno, Carmela
Bordoni, Daniele
Falco, Giuseppe
Rocco, Nicola
A rare case of true carcinosarcoma of the breast
title A rare case of true carcinosarcoma of the breast
title_full A rare case of true carcinosarcoma of the breast
title_fullStr A rare case of true carcinosarcoma of the breast
title_full_unstemmed A rare case of true carcinosarcoma of the breast
title_short A rare case of true carcinosarcoma of the breast
title_sort rare case of true carcinosarcoma of the breast
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802189/
https://www.ncbi.nlm.nih.gov/pubmed/26978126
http://dx.doi.org/10.1016/j.ijscr.2016.03.004
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