Integration of Metabolic Modeling with Gene Co-expression Reveals Transcriptionally Programmed Reactions Explaining Robustness in Mycobacterium tuberculosis

Robustness of metabolic networks is accomplished by gene regulation, modularity, re-routing of metabolites and plasticity. Here, we probed robustness against perturbations of biochemical reactions of M. tuberculosis in the form of predicting compensatory trends. In order to investigate the transcrip...

Descripción completa

Detalles Bibliográficos
Autores principales: Puniya, Bhanwar Lal, Kulshreshtha, Deepika, Mittal, Inna, Mobeen, Ahmed, Ramachandran, Srinivasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802306/
https://www.ncbi.nlm.nih.gov/pubmed/27000948
http://dx.doi.org/10.1038/srep23440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802306/
https://www.ncbi.nlm.nih.gov/pubmed/27000948
http://dx.doi.org/10.1038/srep23440

Ejemplares similares