SIRT3 Deficiency Induces Endothelial Insulin Resistance and Blunts Endothelial-Dependent Vasorelaxation in Mice and Human with Obesity

Recent evidence implicates the critical role of Sirtuin 3 (SIRT3) in the development of many metabolic diseases, but the contribution of SIRT3 to vascular homeostasis remains largely unknown. The aim of this study was to investigate the role of SIRT3 in endothelial insulin resistance and vascular dy...

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Detalles Bibliográficos
Autores principales: Yang, Lu, Zhang, Julei, Xing, Wenjuan, Zhang, Xing, Xu, Jie, Zhang, Haifeng, Chen, Li, Ning, Xiaona, Ji, Gang, Li, Jia, Zhao, Qingchuan, Gao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802313/
https://www.ncbi.nlm.nih.gov/pubmed/27000941
http://dx.doi.org/10.1038/srep23366

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