Cargando…

Mitochondrial redox and pH signaling occurs in axonal and synaptic organelle clusters

Redox switches are important mediators in neoplastic, cardiovascular and neurological disorders. We recently identified spontaneous redox signals in neurons at the single mitochondrion level where transients of glutathione oxidation go along with shortening and re-elongation of the organelle. We now...

Descripción completa

Detalles Bibliográficos
Autores principales:	Breckwoldt, Michael O., Armoundas, Antonis A., Aon, Miguel A., Bendszus, Martin, O’Rourke, Brian, Schwarzländer, Markus, Dick, Tobias P., Kurz, Felix T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802380/ https://www.ncbi.nlm.nih.gov/pubmed/27000952 http://dx.doi.org/10.1038/srep23251

Ejemplares similares

Cardiac mitochondria exhibit dynamic functional clustering
por: Kurz, Felix T., et al.
Publicado: (2014)

Diabetes Increases the Vulnerability of the Cardiac Mitochondrial Network to Criticality
por: Vetter, Larissa, et al.
Publicado: (2020)

Neurofilament Light Regulates Axon Caliber, Synaptic Activity, and Organelle Trafficking in Cultured Human Motor Neurons
por: Sainio, Markus T., et al.
Publicado: (2022)

Function of metabolic and organelle networks in crowded and organized media
por: Aon, Miguel A., et al.
Publicado: (2015)

Interrogating Synaptic Architecture: Approaches for Labeling Organelles and Cytoskeleton Components
por: Reshetniak, Sofiia, et al.
Publicado: (2019)

Axonal Organelles as Molecular Platforms for Axon Growth and Regeneration after Injury
por: Petrova, Veselina, et al.
Publicado: (2021)

Control and Regulation of Integrated Mitochondrial Function in Metabolic and Transport Networks
por: Cortassa, Sonia, et al.
Publicado: (2009)

The movement of membranous organelles in axons. Electron microscopic identification of anterogradely and retrogradely transported organelles
Publicado: (1980)

Clinical Value of Susceptibility Weighted Imaging of Brain Metastases
por: Schwarz, Daniel, et al.
Publicado: (2020)

GTP gamma S inhibits organelle transport along axonal microtubules
Publicado: (1993)

Visualization of the Redox Status of Cytosolic Glutathione Using the Organelle- and Cytoskeleton-Targeted Redox Sensors
por: Hatori, Yuta, et al.
Publicado: (2020)

A Reaction-Diffusion Model of ROS-Induced ROS Release in a Mitochondrial Network
por: Zhou, Lufang, et al.
Publicado: (2010)

GSH or Palmitate Preserves Mitochondrial Energetic/Redox Balance, Preventing Mechanical Dysfunction in Metabolically Challenged Myocytes/Hearts From Type 2 Diabetic Mice
por: Tocchetti, Carlo G., et al.
Publicado: (2012)

Biosensing on acid: fluorescent protein probes for low pH environments
por: Bell, Christopher, et al.
Publicado: (2022)

Glycyl Radical Enzyme-Associated Microcompartments: Redox-Replete Bacterial Organelles
por: Ferlez, Bryan, et al.
Publicado: (2019)

Protocol for Quantitative Analysis of Synaptic Vesicle Clustering in Axons of Cultured Neurons
por: Um, Ji Won, et al.
Publicado: (2020)

Live monitoring of plant redox and energy physiology with genetically encoded biosensors
por: Müller-Schüssele, Stefanie J, et al.
Publicado: (2021)

The needs of a synapse—How local organelles serve synaptic proteostasis
por: Grochowska, Katarzyna M, et al.
Publicado: (2022)

The Coordination of Local Translation, Membranous Organelle Trafficking, and Synaptic Plasticity in Neurons
por: Rajgor, Dipen, et al.
Publicado: (2021)

Rapidly transported organelles containing membrane and cytoskeletal components: their relation to axonal growth
Publicado: (1987)

Products of endocytosis and autophagy are retrieved from axons by regulated retrograde organelle transport
Publicado: (1993)

Coupling axonal mRNA transport and local translation to organelle maintenance and function
por: Vargas, Jose Norberto S., et al.
Publicado: (2022)

Glioblastoma multiforme restructures the topological connectivity of cerebrovascular networks
por: Hahn, Artur, et al.
Publicado: (2019)

Bidirectional organelle transport can occur in cell processes that contain single microtubules
Publicado: (1985)

Bidirectional Ca(2+) signaling occurs between the endoplasmic reticulum and acidic organelles
por: Morgan, Anthony J., et al.
Publicado: (2013)

The Scale-Free Dynamics of Eukaryotic Cells
por: Aon, Miguel A., et al.
Publicado: (2008)

Glutathione/thioredoxin systems modulate mitochondrial H(2)O(2) emission: An experimental-computational study
por: Aon, Miguel Antonio, et al.
Publicado: (2012)

Mechanisms of organelle biogenesis govern stochastic fluctuations in organelle abundance
por: Mukherji, Shankar, et al.
Publicado: (2014)

Kinesin is bound with high affinity to squid axon organelles that move to the plus-end of microtubules
Publicado: (1992)

Local Translation in Axons: When Membraneless RNP Granules Meet Membrane-Bound Organelles
por: Pushpalatha, Kavya Vinayan, et al.
Publicado: (2019)

SYNAPTIC POTENTIAL IN THE MOTOR GIANT AXON OF THE CRAYFISH
por: Hagiwara, Susumu
Publicado: (1958)

Axonal filopodial asymmetry induced by synaptic target
por: Li, Pan P., et al.
Publicado: (2011)

Axonal Noise as a Source of Synaptic Variability
por: Neishabouri, Ali, et al.
Publicado: (2014)

Correction: Mechanisms of organelle biogenesis govern stochastic fluctuations in organelle abundance
por: Mukherji, Shankar, et al.
Publicado: (2015)

Regulation of V-ATPase Activity and Organelle pH by Phosphatidylinositol Phosphate Lipids
por: Banerjee, Subhrajit, et al.
Publicado: (2020)

Dendritic Branch Intersections Are Structurally Regulated Targets for Efficient Axonal Wiring and Synaptic Clustering
por: Pinchas, Monika, et al.
Publicado: (2013)

MAP7 regulates axon morphogenesis by recruiting kinesin-1 to microtubules and modulating organelle transport
por: Tymanskyj, Stephen R, et al.
Publicado: (2018)

Differential axonal trafficking of Neuropeptide Y-, LAMP1-, and RAB7-tagged organelles in vivo
por: Nassal, Joris P, et al.
Publicado: (2022)

The t-SNAREs syntaxin 1 and SNAP-25 are present on organelles that participate in synaptic vesicle recycling
Publicado: (1995)

Mitochondria: hubs of cellular signaling, energetics and redox balance. A rich, vibrant, and diverse landscape of mitochondrial research
por: Aon, Miguel A., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_jjm79ldob58p0s4ika3mh8kf58