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ABCA1‐Mediated Cholesterol Efflux Capacity to Cerebrospinal Fluid Is Reduced in Patients With Mild Cognitive Impairment and Alzheimer's Disease

BACKGROUND: Animal and human studies indicate that ABCA1‐mediated cholesterol transport is important in Alzheimer's disease (AD). We hypothesized that the efficiency of cerebrospinal fluid (CSF) to facilitate ABCA1‐mediated cholesterol efflux would be reduced in participants with mild cognitive...

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Detalles Bibliográficos
Autores principales:	Yassine, Hussein N., Feng, Qingru, Chiang, Jiarong, Petrosspour, Larissa M., Fonteh, Alfred N., Chui, Helena C., Harrington, Michael G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802440/ https://www.ncbi.nlm.nih.gov/pubmed/26873692 http://dx.doi.org/10.1161/JAHA.115.002886

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