Regulation of LRRK2 promoter activity and gene expression by Sp1

BACKGROUND: The dopaminergic neurodegeneration in the nigrostriatal pathway is a prominent neuropathological feature of Parkinson’s disease (PD). Mutations in various genes have been linked to familial PD, and leucine-rich repeat kinase 2 (LRRK2) gene is one of them. LRRK2 is a large complex protein...

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Detalles Bibliográficos
Autores principales: Wang, Juelu, Song, Weihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802577/
https://www.ncbi.nlm.nih.gov/pubmed/27004687
http://dx.doi.org/10.1186/s13041-016-0215-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802577/
https://www.ncbi.nlm.nih.gov/pubmed/27004687
http://dx.doi.org/10.1186/s13041-016-0215-5

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