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Surgical removal and controlled trypsinization of the outer annulus fibrosus improves the bioactivity of the nucleus pulposus in a disc bioreactor culture

BACKGROUND: The maintenance of nucleus pulposus (NP) viability in vitro is difficult. The annulus fibrosus (AF) pathway reflects one nutrient transport channel and may have an important effect on NP viability in disc organ cultures. The present study describes a feasible disc pre-treatment involving...

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Detalles Bibliográficos
Autores principales:	Li, Pei, Shi, Rongmao, Chen, Daosen, Gan, Yibo, Xu, Yuan, Song, Lei, Li, Songtao, Zhou, Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802625/ https://www.ncbi.nlm.nih.gov/pubmed/27000557 http://dx.doi.org/10.1186/s12891-016-0990-2

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