Genetic association and stress mediated down-regulation in trabecular meshwork implicates MPP7 as a novel candidate gene in primary open angle glaucoma

BACKGROUND: Glaucoma is the largest cause of irreversible blindness affecting more than 60 million people globally. The disease is defined as a gradual loss of peripheral vision due to death of Retinal Ganglion Cells (RGC). The RGC death is largely influenced by the rate of aqueous humor production...

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Detalles Bibliográficos
Autores principales: Vishal, Mansi, Sharma, Anchal, Kaurani, Lalit, Alfano, Giovanna, Mookherjee, Suddhasil, Narta, Kiran, Agrawal, Jyoti, Bhattacharya, Iman, Roychoudhury, Susanta, Ray, Jharna, Waseem, Naushin H., Bhattacharya, Shomi S., Basu, Analabha, Sen, Abhijit, Ray, Kunal, Mukhopadhyay, Arijit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802647/
https://www.ncbi.nlm.nih.gov/pubmed/27001270
http://dx.doi.org/10.1186/s12920-016-0177-6

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