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Can we well assess the relative efficacy and tolerability of a new drug versus others at the time of marketing authorization using mixed treatment comparisons? A detailed illustration with escitalopram

OBJECTIVE: To assess the variation of relative efficacy and tolerability of an antidepressant versus others based on both pre-marketing (registration studies) and post-marketing studies versus pre-marketing studies only in patients with major depressive disorder. METHODS: The relative efficacy and t...

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Detalles Bibliográficos
Autores principales: Llorca, Pierre-Michel, Lançon, Christophe, Brignone, Mélanie, Painchault, Caroline, Rive, Benoit, Toumi, Mondher, François, Clément
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Co-Action Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802698/
https://www.ncbi.nlm.nih.gov/pubmed/27123184
http://dx.doi.org/10.3402/jmahp.v3.26776