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The interferon-induced antiviral protein PML (TRIM19) promotes the restriction and transcriptional silencing of lentiviruses in a context-specific, isoform-specific fashion

BACKGROUND: The promyelocytic leukemia (PML) protein, a type I interferon (IFN-I)-induced gene product and a member of the tripartite motif (TRIM) family, modulates the transcriptional activity of viruses belonging to various families. Whether PML has an impact on the replication of HIV-1 has not be...

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Detalles Bibliográficos
Autores principales:	Masroori, Nasser, Merindol, Natacha, Berthoux, Lionel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802722/ https://www.ncbi.nlm.nih.gov/pubmed/27000403 http://dx.doi.org/10.1186/s12977-016-0253-1

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