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Extra pulmonary tuberculosis presenting as fever with massive splenomegaly and pancytopenia

Disseminated tuberculosis is an important differential diagnosis for fever of unknown origin (FUO) and it can present with hepatosplenomegaly and lymphadenopathy and may have meningitis and with hematological abnormalities including pancytopenia or a leukemoid reaction. We report the case of a 13-ye...

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Autores principales: Chandni R., Rajan G., Udayabhaskaran V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802818/
https://www.ncbi.nlm.nih.gov/pubmed/27051579
http://dx.doi.org/10.1016/j.idcr.2016.02.005
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author Chandni R.
Rajan G.
Udayabhaskaran V.
author_facet Chandni R.
Rajan G.
Udayabhaskaran V.
author_sort Chandni R.
collection PubMed
description Disseminated tuberculosis is an important differential diagnosis for fever of unknown origin (FUO) and it can present with hepatosplenomegaly and lymphadenopathy and may have meningitis and with hematological abnormalities including pancytopenia or a leukemoid reaction. We report the case of a 13-year old male who presented with fever, weight loss, pallor and massive splenomegaly with pancytopenia, in whom a bone marrow trephine biopsy showed caseating granulomata, who responded well to antituberculous treatment and has remained healthy on follow up after nine years.
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spelling pubmed-48028182016-04-05 Extra pulmonary tuberculosis presenting as fever with massive splenomegaly and pancytopenia Chandni R. Rajan G. Udayabhaskaran V. IDCases Case Report Disseminated tuberculosis is an important differential diagnosis for fever of unknown origin (FUO) and it can present with hepatosplenomegaly and lymphadenopathy and may have meningitis and with hematological abnormalities including pancytopenia or a leukemoid reaction. We report the case of a 13-year old male who presented with fever, weight loss, pallor and massive splenomegaly with pancytopenia, in whom a bone marrow trephine biopsy showed caseating granulomata, who responded well to antituberculous treatment and has remained healthy on follow up after nine years. Elsevier 2016-03-02 /pmc/articles/PMC4802818/ /pubmed/27051579 http://dx.doi.org/10.1016/j.idcr.2016.02.005 Text en © 2016 Published by Elsevier Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Chandni R.
Rajan G.
Udayabhaskaran V.
Extra pulmonary tuberculosis presenting as fever with massive splenomegaly and pancytopenia
title Extra pulmonary tuberculosis presenting as fever with massive splenomegaly and pancytopenia
title_full Extra pulmonary tuberculosis presenting as fever with massive splenomegaly and pancytopenia
title_fullStr Extra pulmonary tuberculosis presenting as fever with massive splenomegaly and pancytopenia
title_full_unstemmed Extra pulmonary tuberculosis presenting as fever with massive splenomegaly and pancytopenia
title_short Extra pulmonary tuberculosis presenting as fever with massive splenomegaly and pancytopenia
title_sort extra pulmonary tuberculosis presenting as fever with massive splenomegaly and pancytopenia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802818/
https://www.ncbi.nlm.nih.gov/pubmed/27051579
http://dx.doi.org/10.1016/j.idcr.2016.02.005
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