Cargando…
Insights into the role of oxidative stress in the pathology of Friedreich ataxia using peroxidation resistant polyunsaturated fatty acids
Friedreich ataxia is an autosomal recessive, inherited neuro- and cardio-degenerative disorder characterized by progressive ataxia of all four limbs, dysarthria, areflexia, sensory loss, skeletal deformities, and hypertrophic cardiomyopathy. Most disease alleles have a trinucleotide repeat expansion...
Autores principales: | Cotticelli, M. Grazia, Crabbe, Andrew M., Wilson, Robert B., Shchepinov, Mikhail S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802835/ https://www.ncbi.nlm.nih.gov/pubmed/25499576 http://dx.doi.org/10.1016/j.redox.2013.06.004 |
Ejemplares similares
-
The Pathology of Friedreich's Ataxia
por: Rainy, Harry
Publicado: (1905) -
Identification of p38 MAPK as a novel therapeutic target for Friedreich’s ataxia
por: Cotticelli, M. Grazia, et al.
Publicado: (2018) -
The role of oxidative stress in Friedreich's ataxia
por: Lupoli, Federica, et al.
Publicado: (2017) -
Deuterated Polyunsaturated Fatty Acids Reduce Oxidative Stress and Extend the Lifespan of C. elegans
por: Beaudoin-Chabot, Caroline, et al.
Publicado: (2019) -
Skin fibroblast metabolomic profiling reveals that lipid dysfunction predicts the severity of Friedreich’s ataxia
por: Wang, Dezhen, et al.
Publicado: (2022)