Osmolarity: A hidden factor in Nanotoxicology 

In the field of drug delivery, long circulating nanocarriers in the blood have many advantages such as targeted drug delivery and sustained release. Based on our current knowledge, evaluation of the effect of long circulating nanocarriers in the blood stream on osmolarity of plasma has not been repo...

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Autores principales: Moayyedi, Saeid, Mashinchian, Omid, Dinarvand, Rassoul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802901/
https://www.ncbi.nlm.nih.gov/pubmed/27001042
http://dx.doi.org/10.1186/s40199-016-0146-9
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author Moayyedi, Saeid
Mashinchian, Omid
Dinarvand, Rassoul
author_facet Moayyedi, Saeid
Mashinchian, Omid
Dinarvand, Rassoul
author_sort Moayyedi, Saeid
collection PubMed
description In the field of drug delivery, long circulating nanocarriers in the blood have many advantages such as targeted drug delivery and sustained release. Based on our current knowledge, evaluation of the effect of long circulating nanocarriers in the blood stream on osmolarity of plasma has not been reported before. In this study, osmotic pressure developed by some commercially available nanocarriers was estimated based on Van't Hoff equation. It is noteworthy that theoretically, nanocarriers do not have any significant effect on osmolarity of plasma. However, it is worth being evaluated experimentally in order to be taken into account in future studies.
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spelling pubmed-48029012016-03-23 Osmolarity: A hidden factor in Nanotoxicology  Moayyedi, Saeid Mashinchian, Omid Dinarvand, Rassoul Daru Letter to the Editor In the field of drug delivery, long circulating nanocarriers in the blood have many advantages such as targeted drug delivery and sustained release. Based on our current knowledge, evaluation of the effect of long circulating nanocarriers in the blood stream on osmolarity of plasma has not been reported before. In this study, osmotic pressure developed by some commercially available nanocarriers was estimated based on Van't Hoff equation. It is noteworthy that theoretically, nanocarriers do not have any significant effect on osmolarity of plasma. However, it is worth being evaluated experimentally in order to be taken into account in future studies. BioMed Central 2016-03-22 /pmc/articles/PMC4802901/ /pubmed/27001042 http://dx.doi.org/10.1186/s40199-016-0146-9 Text en © Moayyedi et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Letter to the Editor
Moayyedi, Saeid
Mashinchian, Omid
Dinarvand, Rassoul
Osmolarity: A hidden factor in Nanotoxicology 
title Osmolarity: A hidden factor in Nanotoxicology 
title_full Osmolarity: A hidden factor in Nanotoxicology 
title_fullStr Osmolarity: A hidden factor in Nanotoxicology 
title_full_unstemmed Osmolarity: A hidden factor in Nanotoxicology 
title_short Osmolarity: A hidden factor in Nanotoxicology 
title_sort osmolarity: a hidden factor in nanotoxicology 
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802901/
https://www.ncbi.nlm.nih.gov/pubmed/27001042
http://dx.doi.org/10.1186/s40199-016-0146-9
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AT dinarvandrassoul osmolarityahiddenfactorinnanotoxicology

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