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Endothelium-Derived 5-Methoxytryptophan Protects Endothelial Barrier Function by Blocking p38 MAPK Activation

The endothelial junction is tightly controlled to restrict the passage of blood cells and solutes. Disruption of endothelial barrier function by bacterial endotoxins, cytokines or growth factors results in inflammation and vascular damage leading to vascular diseases. We have identified 5-methoxytry...

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Detalles Bibliográficos
Autores principales:	Chu, Ling-Yun, Wang, Yi-Fu, Cheng, Huei-Hsuan, Kuo, Cheng-Chin, Wu, Kenneth K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803234/ https://www.ncbi.nlm.nih.gov/pubmed/27002329 http://dx.doi.org/10.1371/journal.pone.0152166

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