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The hypocretin/orexin system in sleep disorders: preclinical insights and clinical progress

Much of the understanding of the hypocretin/orexin (HCRT/OX) system in sleep–wake regulation came from narcolepsy–cataplexy research. The neuropeptides hypocretin-1 and -2/orexin-A and -B (HCRT-1 and -2/OX-A and -B, respectively), as we know, are intimately involved in the regulation wakefulness. Th...

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Detalles Bibliográficos
Autores principales: Chow, Matthew, Cao, Michelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803263/
https://www.ncbi.nlm.nih.gov/pubmed/27051324
http://dx.doi.org/10.2147/NSS.S76711

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