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Geminin deletion in mouse oocytes results in impaired embryo development and reduced fertility

Geminin controls proper centrosome duplication, cell division, and differentiation. We investigated the function of geminin in oogenesis, fertilization, and early embryo development by deleting the geminin gene in oocytes from the primordial follicle stage. Oocyte-specific disruption of geminin resu...

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Detalles Bibliográficos
Autores principales: Ma, Xue-Shan, Lin, Fei, Wang, Zhong-Wei, Hu, Meng-Wen, Huang, Lin, Meng, Tie-Gang, Jiang, Zong-Zhe, Schatten, Heide, Wang, Zhen-Bo, Sun, Qing-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803303/
https://www.ncbi.nlm.nih.gov/pubmed/26764091
http://dx.doi.org/10.1091/mbc.E15-06-0346