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Geminin deletion in mouse oocytes results in impaired embryo development and reduced fertility
Geminin controls proper centrosome duplication, cell division, and differentiation. We investigated the function of geminin in oogenesis, fertilization, and early embryo development by deleting the geminin gene in oocytes from the primordial follicle stage. Oocyte-specific disruption of geminin resu...
Autores principales: | Ma, Xue-Shan, Lin, Fei, Wang, Zhong-Wei, Hu, Meng-Wen, Huang, Lin, Meng, Tie-Gang, Jiang, Zong-Zhe, Schatten, Heide, Wang, Zhen-Bo, Sun, Qing-Yuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803303/ https://www.ncbi.nlm.nih.gov/pubmed/26764091 http://dx.doi.org/10.1091/mbc.E15-06-0346 |
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