Filling in the Gap of Human Chromosome 4: Single Molecule Real Time Sequencing of Macrosatellite Repeats in the Facioscapulohumeral Muscular Dystrophy Locus

A majority of facioscapulohumeral muscular dystrophy (FSHD) is caused by contraction of macrosatellite repeats called D4Z4 that are located in the subtelomeric region of human chromosome 4q35. Sequencing the FSHD locus has been technically challenging due to its long size and nearly identical nature...

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Detalles Bibliográficos
Autores principales: Morioka, Masaki Suimye, Kitazume, Miwako, Osaki, Ken, Wood, Jonathan, Tanaka, Yujiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803325/
https://www.ncbi.nlm.nih.gov/pubmed/27002334
http://dx.doi.org/10.1371/journal.pone.0151963

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